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T3, or triiodothyronine, is an active thyroid hormone that significantly affects the rate of metabolism. It is used medically for thyroid disorders, such as hypothyroidism. In bodybuilding, it is sometimes abused during cutting phases, which is associated with serious risks. 

How T3 affects fat burning 

• increases basal metabolism 

• increases energy expenditure even at rest 

• accelerates lipolysis and mobilization of fat stores 

• can increase caloric expenditure even with the same food intake 

• affects the metabolism of carbohydrates and proteins 

Risk of muscle loss 

T3 not only increases fat loss, but if used incorrectly, it can also promote protein breakdown, increasing the risk of muscle loss. 

Health risks 

Use without medical indication can be dangerous: 

• heart palpitations and tachycardia 

• heart rhythm disorders 

• high blood pressure 

• muscle loss 

• nervousness and tremors 

• long-term disruption of the thyroid gland’s own function 

Combinations in bodybuilding 

In some bodybuilding circles, T3 is mentioned during the “cutting” phase with anabolic steroids, stimulants, growth hormone or clenbuterol. Such combinations significantly increase the risk of cardiovascular complications, nervous system overload and long-term hormonal consequences. 

Summary 

• T3 can strongly increase metabolism and accelerate fat loss. 

• It also increases the risk of muscle loss. 

• Improper use can cause serious health consequences. 

• Combining it with other performance-enhancing substances is extremely risky.